­
­
­
­

Inventi Impact: Pharm Tech

Articles

  • Inventi:ppt/27092/18
    Enhancing Antidepressant Effect of Poloxamer/Chitosan Thermosensitive Gel Containing\nCurcumin-Cyclodextrin Inclusion Complex
    01-Jan-1970 Research 2018 : October - December
    Ye Zhang

    Poor solubility and bioavailability are limiting factors for the clinical application of curcumin. This study seeks to develop\npoloxamer/chitosan thermosensitive gel containing curcumin-cyclodextrin inclusion complex with enhanced brain bioavailability\nand antidepressant effect. The optimized gel had shorter gelation time and produced sustained release in vitro characterized\nwith non-Fickian diffusion. Pharmacokinetics of gel were evaluated using male Sprague-Dawley rats receiving 240

    How to Cite this Article
    Ye Zhang, â??Enhancing Antidepressant Effect\nof Poloxamer/Chitosan Thermosensitive Gel Containing Curcumin-\nCyclodextrin Inclusion Complex,â? International Journal of Polymer\nScience, vol. 2018, Article ID 3041417, 8 pages, 2018. https://\ndoi.org/10.1155/2018/3041417, https://creativecommons.org/\nlicenses/by/4.0/.
    Download Full Text